Mammograms showing healthy (left) and (right) cancerous breast. Courtesy of the National Cancer Institute.
Can having too many menstrual cycles give you breast cancer? That’s what one might conclude from two unrelated articles that appeared in national newspapers this week.
First was Nicholas D. Kristof’s Op-Ed in the New York Times. Kristof had recently attended a symposium exploring whether certain common chemicals are linked to breast cancer and other ailments. The role of estrogen – both the real thing our bodies produce and the pseudo-estrogens – in breast cancer was his major example.
The real thing:
One theory starts with the well-known fact that women with more lifetime menstrual cycles are at greater risk for breast cancer, because they’re exposed to more estrogen. For example, a woman who began menstruating before 12 has a 30 percent greater risk of breast cancer than one who began at 15 or later.
The pseudo-estrogens:
One class of chemicals that creates concern — although the evidence is not definitive — is endocrine disruptors, which are often similar to estrogen and may fool the body into setting off hormonal changes. This used to be a fringe theory, but it is now being treated with great seriousness by the Endocrine Society the professional association of hormone specialists in the United States. …These endocrine disruptors are found in everything from certain plastics to various cosmetics.
(Do you ever wonder, like I do, why the birth control pill is not considered an ‘endocrine disruptor’ when that is exactly what it is?)
The second mention of the connection between too many periods and breast cancer came in dietician Leslie Beck’s Food For Thought column in Canada’s Globe and Mail. She was reporting on a new study showing that women with breast cancer need not shun soy:
By acting like weak forms of the body’s own estrogen, some experts have worried that soy isoflavones could possibly promote cancer growth. That’s because certain risk factors for breast cancer, such as beginning your menstrual period before age 12 or starting menopause after 55, are related to the length of time breast cells are exposed to the body’s own circulating estrogen. It’s thought that estrogen can promote the growth of breast cancer cells.
It’s reasonable to think that the both the writers and readers of these articles (and the many more that have surely mentioned this connection) might assume from this information that too many menstrual cycles means too much estrogen, therefore too many menstrual cycles must be a bad thing. What they don’t know is that not all menstrual cycles are created equal. It’s not necessarily about quantity, it’s about quality.
Common belief is that all menstrual cycles are ovulatory. (Unless, of course, you are using a hormonal birth control method that suppress ovulation like the pill, patch or ring.) In other words, the assumption is that if get your period you must have ovulated. This assumption is challenged by UBC endocrinolgist Jerilynn Prior, MD, and Scientific Director of the Centre for Menstual Cycle and Ovulation Research (CeMCOR). In her article Is Ovulation (and are normal Progesterone levels) Important for the Health of Women?, Dr. Prior has this to say about the connection between ovulation, menstruation and breast cancer:
